According to the National Institute on Aging (NIA) (NIA), the new vaccine targets senescent cells that have stopped multiplying due to damage or stress, but do not die. These cells accumulate as we age and release compounds that cause inflammation and thus damage nearby healthy cells.
The vaccine can be given to people about 50 years old. This will avoid the accumulation of senescent cells. The vaccinated person’s immune system will be trained to look for senescent cells and destroy them in situ. Scientists did not notice any side effects in the vaccinated mice.
The researchers noted that, in theory, the same approach would work with humans. But the big question is whether this vaccine will be safe. To understand this, scientists will need to do more research in animals, including primates, and then in humans.