Now the problem of organizing a healthy diet is becoming more and more urgent. At the same time, it is important to know what substances in our body are involved in the digestion of food, and also signal that we want to eat or, conversely, have already eaten enough dishes. The hormone is responsible for the feeling of hunger and satiety. ghrelin.
Scientists discovered this substance in 1999. The synthesis of ghrelin is carried out due to the work of the endocrine cells of the stomach, cells of the hypothalamus, kidneys. There are also active and inactive forms of the hormone, and both play an important role in appetite and in regulating the amount of food eaten.
Ghrelin interacts with organ receptors found throughout the body. In particular, in the stomach, intestines, brain, etc. In addition, there is a special group of brain receptors (endocannabinoid system), which is also responsible for the development of appetite. Experiments on mice have shown that the introduction of ghrelin increases the amount of food eaten and can lead to weight gain.