Wednesday, December 7, 2022
HomeDigit NewsMaterial for 3D printing of biodegradable implants created in Russia

Material for 3D printing of biodegradable implants created in Russia

Resins for 3D printing of biomedical products were synthesized in the Laboratory of Polymer Materials of the National Research Center “Kurchatov Institute”. This will allow in the future to create personalized implants for a particular patient, scientists say. Biodegradable polymers are a strong and elastic material that can be used to create systems for controlled delivery of drugs to a target organ, suture surgical materials, various bone fixators (screws, pins, rods), as well as materials for tissue engineering. After performing its function, for example, fusion of bone tissue, the biodegradable implant decomposes in the human body to non-toxic compounds – carbon dioxide and water – and will be completely eliminated from the body.

But in order to create complex-shaped implants, for example, made for a specific patient, 3D printing technologies are needed, which will require special polymer resins. Their composition determines the possibility of regulating the properties of medical products – mechanical characteristics and decay rate in the human body. Resins for 3D printing of medical products based on biocompatible biodegradable polyesters — lactide and caprolactone — were synthesized at the Kurchatov Institute. Then, with resins of different compositions, standard samples for testing were printed on a bioprinter.

The test results showed that oligomers (substances whose molecules contain chains of a small number of identical units) have a lower viscosity, in contrast to high-molecular analogues. This allows the use of narrower nozzles of a 3D printer when printing, which significantly increases the accuracy when creating implants, the scientists note. In addition, implants can be printed with low-viscosity resins at significantly lower temperatures, so drugs can be added to them without fear of losing their medicinal properties. The result will be an implant filled with drugs that accelerate healing, or antibiotics that prevent bacteria from multiplying, the press service of the institute said.

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