Specialists from Duke and North Carolina Universities analyzed blood samples from two patients. One of them was infected with the original SARS-CoV-1 virus more than 17 years ago, the other has been ill with COVID-19 today. They managed to find more than 1.7 thousand antibodies. 50 of them were able to bind to both SARS-CoV-1 and SARS-CoV-2. One of these cross-antibodies, the code for which is DH1047, has proven to be particularly effective as it is able to bind to a variety of coronaviruses that infect animals.
In experiments on mice, the researchers found that the antibody effectively neutralizes both SARS-COV-1 and COVID-19 and its various variants. The found antibody was able to reduce the severity of disease not only before it was introduced into the body, but also after. According to the researchers, DH1047 could serve as the basis for universal vaccines against coronavirus in the future.